![]() It increases the risk of adverse pregnancy outcomes, such as preterm birth, cesarean delivery, macrosomia, postpartum type 2 diabetes mellitus, and metabolic diseases in offspring. ![]() Gestational diabetes mellitus (GDM) is a common metabolic complication of pregnancy defined as glucose intolerance first identified during pregnancy. Therefore, the optimal BMI in early pregnancy is the key to preventing GDM. ConclusionsīMI in early pregnancy was a risk factor for GDM, while BMI gain before GDM screening was not associated with the risk of GDM. After adjusting on early pregnancy BMI and other confounding factors, the effect of BMI gain was no longer significant ( AOR 1.029, 95% CI 0.999–1.061), as well as weight gain ( AOR 1.006, 95% CI 0.995–1.018) and GWG categories (insufficient: AOR 1.016, 95% CI 0.911–1.133 excessive: AOR 1.044, 95% CI 0.957–1.138). And BMI gain was associated with a decreased risk of GDM in unadjusted univariate analysis ( OR 0.895, 95% CI 0.869–0.922). Early pregnancy BMI was a risk factor for GDM ( OR 1.131, 95% CI 1.122–1.139). BMI gain has no significant differences between the GDM and non-GDM groups at any early pregnancy BMI categories (each of 2 kg/m 2), as well as weight gain ( P > 0.05). ResultsĪ total of 41,845 pregnant women were included in the final analysis (GDM group, n = 4257 vs. Logistic regression was applied to determine the significance of variables with GDM. GWG was evaluated according to the IOM guidelines. We compared gestational BMI change and GWG in the two groups from early pregnancy to GDM screening. According to the results of GDM screening at 24–28 weeks of gestation, pregnancies were divided into the GDM group and the non-GDM group. ![]() This study investigated the BMI change of pregnant women based on a retrospective study covering all communities in Tianjin, China. ![]() Understanding BMI changes during pregnancy may provide new evidence for the prevention of GDM. Compared to body weight, BMI has the advantage that it considers height during the whole course of pregnancy. But due to the heterogeneity of diagnosis and treatment and the potential effect of GDM treatment on GWG, the association between the two has not been thoroughly clarified. It is associated with maternal body mass index (BMI) and may be associated with gestational weight gain (GWG). Gestational diabetes mellitus (GDM) is associated with adverse health consequences for women and their offspring. ![]()
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